Tacrine-coumarin and Tacrine-7-chloroquinoline Hybrids with Thiourea Linkers: Cholinesterase Inhibition Properties, Kinetic Study, Molecular Docking and Permeability Assay for Blood-brain Barrier.

Hamulakova, Slavka

Tacrine-coumarin and Tacrine-7-chloroquinoline Hybrids with Thiourea Linkers: Cholinesterase Inhibition Properties, Kinetic Study, Molecular Docking and Permeability Assay for Blood-brain Barrier. [electronic resource] - Current Alzheimer research 2018 - 1096-1105 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1875-5828

10.2174/1567205015666180711110750 doi


Animals
Blood-Brain Barrier--drug effects
Cholinesterase Inhibitors--chemistry
Coumarins--chemistry
Humans
Kinetics
Models, Molecular
Molecular Docking Simulation
Permeability--drug effects
Structure-Activity Relationship
Tacrine--chemistry
Thiourea--chemistry