Pharmacological and toxicological activity of RSD921, a novel sodium channel blocker.

Walker, M J A

Pharmacological and toxicological activity of RSD921, a novel sodium channel blocker. [electronic resource] - Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Oct 2018 - 510-522 p. digital

Publication Type: Journal Article

1950-6007

10.1016/j.biopha.2018.06.157 doi


Action Potentials
Administration, Intravenous
Anesthetics, Local--administration & dosage
Animals
Anti-Arrhythmia Agents--administration & dosage
Antihypertensive Agents--pharmacology
Arrhythmias, Cardiac--etiology
Blood Pressure--drug effects
Disease Models, Animal
Dogs
Dose-Response Relationship, Drug
Female
Guinea Pigs
Heart Rate--drug effects
Humans
Injections, Intradermal
Isolated Heart Preparation
Male
Mice
Myocytes, Cardiac--drug effects
Neural Conduction--drug effects
Pain Threshold--drug effects
Papio
Pyrroles--pharmacology
Rats
Rats, Sprague-Dawley
Sodium Channel Blockers--administration & dosage
Sodium Channels--drug effects
Thiophenes--pharmacology
Time Factors
Xenopus laevis