Nonclinical and human pharmacology of the potent and selective topical retinoic acid receptor-γ agonist trifarotene.

Aubert, J

Nonclinical and human pharmacology of the potent and selective topical retinoic acid receptor-γ agonist trifarotene. [electronic resource] - The British journal of dermatology 08 2018 - 442-456 p. digital

Publication Type: Clinical Trial; Journal Article

1365-2133

10.1111/bjd.16719 doi


Acne Vulgaris--drug therapy
Administration, Cutaneous
Animals
Biopsy
Cell Differentiation--drug effects
Cell Line
Dermatologic Agents--pharmacology
Disease Models, Animal
Drug Evaluation, Preclinical
Drug Stability
Gene Expression--drug effects
Gene Expression Profiling
Humans
Keratinocytes--drug effects
Mice
Microsomes, Liver
Receptors, Retinoic Acid--agonists
Retinoids--pharmacology
Skin
Skin Pigmentation--drug effects
Tissue Culture Techniques
Retinoic Acid Receptor gamma