Polyphyllin I inhibits invasion and epithelial-mesenchymal transition via CIP2A/PP2A/ERK signaling in prostate cancer.

Liu, Xuewen

Polyphyllin I inhibits invasion and epithelial-mesenchymal transition via CIP2A/PP2A/ERK signaling in prostate cancer. [electronic resource] - International journal of oncology Sep 2018 - 1279-1288 p. digital

Publication Type: Journal Article

1791-2423

10.3892/ijo.2018.4464 doi


Animals
Antineoplastic Agents--pharmacology
Autoantigens--metabolism
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Diosgenin--analogs & derivatives
Down-Regulation
Drug Evaluation, Preclinical
Epithelial-Mesenchymal Transition--drug effects
Extracellular Signal-Regulated MAP Kinases--metabolism
Humans
Intracellular Signaling Peptides and Proteins
Male
Melanthiaceae--chemistry
Membrane Proteins--metabolism
Mice
Mice, Nude
Neoplasm Invasiveness--prevention & control
Phosphorylation--drug effects
Prostatic Neoplasms--drug therapy
Protein Phosphatase 2--metabolism
Signal Transduction--drug effects
Xenograft Model Antitumor Assays