Selective BH3-mimetics targeting BCL-2, BCL-XL or MCL-1 induce severe mitochondrial perturbations.

Henz, Kristina

Selective BH3-mimetics targeting BCL-2, BCL-XL or MCL-1 induce severe mitochondrial perturbations. [electronic resource] - Biological chemistry 01 2019 - 181-185 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1437-4315

10.1515/hsz-2018-0233 doi


Apoptosis
Caspases--metabolism
Enzyme Activation
Humans
Mitochondria--drug effects
Molecular Mimicry
Myeloid Cell Leukemia Sequence 1 Protein--drug effects
Proto-Oncogene Proteins c-bcl-2--drug effects
bcl-X Protein--drug effects