Depletion of A-type lamins and Lap2α reduces 53BP1 accumulation at UV-induced DNA lesions and Lap2α protein is responsible for compactness of irradiated chromatin.
Bártová, Eva
Depletion of A-type lamins and Lap2α reduces 53BP1 accumulation at UV-induced DNA lesions and Lap2α protein is responsible for compactness of irradiated chromatin. [electronic resource] - Journal of cellular biochemistry 11 2018 - 8146-8162 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1097-4644
10.1002/jcb.26770 doi
Animals
Cell Line, Transformed
Chromatin--chemistry
DNA Damage
DNA Repair
DNA-Binding Proteins--deficiency
Embryo, Mammalian
Fibroblasts--cytology
Fluorescence Recovery After Photobleaching
Gamma Rays
Gene Expression Regulation
Genes, Reporter
Histones--genetics
Lamin Type A--deficiency
Luminescent Proteins--genetics
Membrane Proteins--deficiency
Mice
Recombinant Fusion Proteins--genetics
Signal Transduction
Tumor Suppressor p53-Binding Protein 1--genetics
Ultraviolet Rays
Red Fluorescent Protein
Depletion of A-type lamins and Lap2α reduces 53BP1 accumulation at UV-induced DNA lesions and Lap2α protein is responsible for compactness of irradiated chromatin. [electronic resource] - Journal of cellular biochemistry 11 2018 - 8146-8162 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1097-4644
10.1002/jcb.26770 doi
Animals
Cell Line, Transformed
Chromatin--chemistry
DNA Damage
DNA Repair
DNA-Binding Proteins--deficiency
Embryo, Mammalian
Fibroblasts--cytology
Fluorescence Recovery After Photobleaching
Gamma Rays
Gene Expression Regulation
Genes, Reporter
Histones--genetics
Lamin Type A--deficiency
Luminescent Proteins--genetics
Membrane Proteins--deficiency
Mice
Recombinant Fusion Proteins--genetics
Signal Transduction
Tumor Suppressor p53-Binding Protein 1--genetics
Ultraviolet Rays
Red Fluorescent Protein