Synthesis and biological evaluation of novel 2-oxo-1,2-dihydroquinoline-4-carboxamide derivatives for the treatment of esophageal squamous cell carcinoma.

Shahin, Mai I

Synthesis and biological evaluation of novel 2-oxo-1,2-dihydroquinoline-4-carboxamide derivatives for the treatment of esophageal squamous cell carcinoma. [electronic resource] - European journal of medicinal chemistry Jul 2018 - 516-530 p. digital

Publication Type: Journal Article

1768-3254

10.1016/j.ejmech.2018.05.042 doi


Antineoplastic Agents--chemical synthesis
Carcinoma, Squamous Cell--drug therapy
Cell Cycle--drug effects
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Esophageal Neoplasms--drug therapy
Esophageal Squamous Cell Carcinoma
Humans
Molecular Structure
Quinolines--chemical synthesis
Structure-Activity Relationship
Tumor Cells, Cultured