Genistein rescues hypoxia-induced pulmonary arterial hypertension through estrogen receptor and β-adrenoceptor signaling.

Zhang, Ming

Genistein rescues hypoxia-induced pulmonary arterial hypertension through estrogen receptor and β-adrenoceptor signaling. [electronic resource] - The Journal of nutritional biochemistry 08 2018 - 110-118 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-4847

10.1016/j.jnutbio.2018.04.016 doi


Animals
Cell Hypoxia
Cell Size--drug effects
Cells, Cultured
Chick Embryo
Genistein--pharmacology
Hypertension, Pulmonary--drug therapy
Hypoxia-Inducible Factor 1, alpha Subunit--metabolism
Muscle, Smooth, Vascular--drug effects
Pulmonary Artery--cytology
Reactive Oxygen Species--metabolism
Receptors, Adrenergic, beta--metabolism
Receptors, Estrogen--metabolism
Signal Transduction--drug effects