Quantitative Translational Analysis of Brain Kynurenic Acid Modulation via Irreversible Kynurenine Aminotransferase II Inhibition.

Chang, Cheng

Quantitative Translational Analysis of Brain Kynurenic Acid Modulation via Irreversible Kynurenine Aminotransferase II Inhibition. [electronic resource] - Molecular pharmacology 08 2018 - 823-833 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-0111

10.1124/mol.118.111625 doi


Animals
Brain--metabolism
Brain Chemistry--drug effects
Cells, Cultured
Chromatography, Liquid
Enzyme Inhibitors--administration & dosage
Female
Half-Life
Humans
Kynurenic Acid--analysis
Macaca fascicularis
Male
Pyrazoles--administration & dosage
Rats
Tandem Mass Spectrometry
Transaminases--antagonists & inhibitors