Serum derived from ulcerative colitis mouse changes the metabolism of the fluorescent substrate by P450 depending on the degree of disease progression.

Yamamoto, Ryuichi

Serum derived from ulcerative colitis mouse changes the metabolism of the fluorescent substrate by P450 depending on the degree of disease progression. [electronic resource] - Chemico-biological interactions Jun 2018 - 88-98 p. digital

Publication Type: Journal Article

1872-7786

10.1016/j.cbi.2018.05.012 doi


Animals
Area Under Curve
Biomarkers--blood
Colitis, Ulcerative--chemically induced
Cytochrome P-450 CYP2C19--blood
Cytochrome P-450 CYP2E1--blood
Cytochrome P-450 Enzyme System--blood
Dextran Sulfate--toxicity
Disease Progression
Female
Fluorescent Dyes--chemistry
Humans
Liver--metabolism
Mice
Mice, Inbred C57BL
ROC Curve
Real-Time Polymerase Chain Reaction
Substrate Specificity