Droplet digital PCR detects high rate of TP53 R249S mutants in cell-free DNA of middle African patients with hepatocellular carcinoma.

Marchio, Agnès

Droplet digital PCR detects high rate of TP53 R249S mutants in cell-free DNA of middle African patients with hepatocellular carcinoma. [electronic resource] - Clinical and experimental medicine Aug 2018 - 421-431 p. digital

Publication Type: Journal Article

1591-9528

10.1007/s10238-018-0502-9 doi


Adolescent
Adult
Aflatoxin B1--toxicity
Aged
Aged, 80 and over
Cameroon
Carcinoma, Hepatocellular--chemically induced
Case-Control Studies
Cell-Free Nucleic Acids--blood
Central African Republic
DNA, Viral--genetics
Female
Gene Expression
Hepatitis B Surface Antigens--blood
Hepatitis B virus--genetics
Hepatitis B, Chronic--diagnosis
Humans
Liver Neoplasms--chemically induced
Male
Middle Aged
Mutation Rate
Polymerase Chain Reaction--methods
Tumor Suppressor Protein p53--blood
Viral Load
alpha-Fetoproteins--genetics