The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability.

Paredes, Silvana

The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability. [electronic resource] - The Journal of biological chemistry 07 2018 - 11242-11250 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1083-351X

10.1074/jbc.AC118.003325 doi


Bone Neoplasms--genetics
Cellular Senescence
DNA, Ribosomal--genetics
Epigenesis, Genetic
Gene Expression Regulation, Neoplastic
Genomic Instability
Humans
Osteosarcoma--genetics
Sirtuins--genetics
Transcription, Genetic
Tumor Cells, Cultured