Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis.

Michailidou, Iliana

Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis. [electronic resource] - Acta neuropathologica communications 05 2018 - 36 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2051-5960

10.1186/s40478-018-0536-y doi


Animals
Anti-Inflammatory Agents--chemistry
Axons--drug effects
Complement Activation
Complement Membrane Attack Complex--antagonists & inhibitors
Disease Models, Animal
Encephalitis--drug therapy
Encephalomyelitis, Autoimmune, Experimental--complications
Exoribonucleases--therapeutic use
Male
Mice
Microscopy, Electron
Models, Biological
Peptides, Cyclic--therapeutic use
RNA, Messenger--metabolism
Receptor, Anaphylatoxin C5a--antagonists & inhibitors
Synaptophysin--metabolism