Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice.
Kim, Kook Hwan
Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice. [electronic resource] - Scientific reports 05 2018 - 6789 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2045-2322
10.1038/s41598-018-25098-0 doi
Actins--genetics
Animals
Choline Deficiency--genetics
Collagen Type I--genetics
Collagen Type I, alpha 1 Chain
Diet--adverse effects
Disease Models, Animal
Endoplasmic Reticulum Stress--genetics
Gene Expression Regulation
Growth Differentiation Factor 15--deficiency
Hepatic Stellate Cells--metabolism
Humans
Liver--metabolism
Liver Cirrhosis--etiology
Male
Methionine--deficiency
Mice
Mice, Inbred C57BL
Mice, Knockout
Non-alcoholic Fatty Liver Disease--etiology
Osteopontin--genetics
Primary Cell Culture
Signal Transduction
Tissue Inhibitor of Metalloproteinase-1--genetics
Transcription Factor CHOP--genetics
Transforming Growth Factor beta1--genetics
Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice. [electronic resource] - Scientific reports 05 2018 - 6789 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2045-2322
10.1038/s41598-018-25098-0 doi
Actins--genetics
Animals
Choline Deficiency--genetics
Collagen Type I--genetics
Collagen Type I, alpha 1 Chain
Diet--adverse effects
Disease Models, Animal
Endoplasmic Reticulum Stress--genetics
Gene Expression Regulation
Growth Differentiation Factor 15--deficiency
Hepatic Stellate Cells--metabolism
Humans
Liver--metabolism
Liver Cirrhosis--etiology
Male
Methionine--deficiency
Mice
Mice, Inbred C57BL
Mice, Knockout
Non-alcoholic Fatty Liver Disease--etiology
Osteopontin--genetics
Primary Cell Culture
Signal Transduction
Tissue Inhibitor of Metalloproteinase-1--genetics
Transcription Factor CHOP--genetics
Transforming Growth Factor beta1--genetics