Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform.
Pant, Shishir M
Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform. [electronic resource] - Journal of medicinal chemistry 05 2018 - 4335-4347 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/acs.jmedchem.7b01698 doi
Breast Neoplasms--drug therapy
Cell Proliferation--drug effects
Drug Design
Enzyme Inhibitors--chemistry
Female
High-Throughput Screening Assays--standards
Humans
Models, Molecular
Molecular Structure
Protein Conformation
Serine Endopeptidases--chemistry
Tumor Cells, Cultured
Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform. [electronic resource] - Journal of medicinal chemistry 05 2018 - 4335-4347 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/acs.jmedchem.7b01698 doi
Breast Neoplasms--drug therapy
Cell Proliferation--drug effects
Drug Design
Enzyme Inhibitors--chemistry
Female
High-Throughput Screening Assays--standards
Humans
Models, Molecular
Molecular Structure
Protein Conformation
Serine Endopeptidases--chemistry
Tumor Cells, Cultured