Single CpG hypermethylation, allele methylation errors, and decreased expression of multiple tumor suppressor genes in normal body cells of mutation-negative early-onset and high-risk breast cancer patients.

Böck, Julia

Single CpG hypermethylation, allele methylation errors, and decreased expression of multiple tumor suppressor genes in normal body cells of mutation-negative early-onset and high-risk breast cancer patients. [electronic resource] - International journal of cancer 09 2018 - 1416-1425 p. digital

Publication Type: Journal Article

1097-0215

10.1002/ijc.31526 doi


Adult
Alleles
Biomarkers, Tumor--genetics
Breast--metabolism
Breast Neoplasms--diagnosis
Case-Control Studies
CpG Islands--genetics
DNA Methylation
Epigenesis, Genetic
Female
Gene Expression Regulation, Neoplastic
Genetic Predisposition to Disease
Humans
Mutation
Prognosis
Promoter Regions, Genetic
Risk Factors
Tumor Suppressor Proteins--genetics