Treatment of Multidrug-Resistant Leukemia Cells by Novel Artemisinin-, Egonol-, and Thymoquinone-Derived Hybrid Compounds.

Gruber, Lisa

Treatment of Multidrug-Resistant Leukemia Cells by Novel Artemisinin-, Egonol-, and Thymoquinone-Derived Hybrid Compounds. [electronic resource] - Molecules (Basel, Switzerland) Apr 2018

Publication Type: Journal Article

1420-3049

10.3390/molecules23040841 doi


ATP-Binding Cassette Transporters--metabolism
Antineoplastic Agents--chemistry
Artemisinins--chemistry
Benzoquinones--chemistry
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Doxorubicin--pharmacology
Drug Resistance, Multiple--drug effects
Drug Resistance, Neoplasm--drug effects
Gene Expression Regulation, Neoplastic--drug effects
Humans
Leukemia--drug therapy
Molecular Docking Simulation
Succinates--chemistry