DupuytrEn Treatment EffeCtiveness Trial (DETECT): a protocol for prospective, randomised, controlled, outcome assessor-blinded, three-armed parallel 1:1:1, multicentre trial comparing the effectiveness and cost of collagenase clostridium histolyticum, percutaneous needle fasciotomy and limited fasciectomy as short-term and long-term treatment strategies in Dupuytren's contracture.

Räisänen, Mikko P

DupuytrEn Treatment EffeCtiveness Trial (DETECT): a protocol for prospective, randomised, controlled, outcome assessor-blinded, three-armed parallel 1:1:1, multicentre trial comparing the effectiveness and cost of collagenase clostridium histolyticum, percutaneous needle fasciotomy and limited fasciectomy as short-term and long-term treatment strategies in Dupuytren's contracture. [electronic resource] - BMJ open 03 2018 - e019054 p. digital

Publication Type: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

2044-6055

10.1136/bmjopen-2017-019054 doi


Adult
Aged
Aged, 80 and over
Collagenases--therapeutic use
Contracture--drug therapy
Cost-Benefit Analysis
Dupuytren Contracture--drug therapy
Fasciotomy--methods
Female
Hand--pathology
Humans
Male
Microbial Collagenase--therapeutic use
Middle Aged
Needles
Orthopedic Procedures
Prospective Studies
Research Design
Time Factors
Treatment Outcome
Young Adult