Is tranexamic acid toxic to articular cartilage when administered topically? What is the safe dose?

Parker, J D

Is tranexamic acid toxic to articular cartilage when administered topically? What is the safe dose? [electronic resource] - The bone & joint journal 03 2018 - 404-412 p. digital

Publication Type: Journal Article

2049-4408

10.1302/0301-620X.100B3.BJJ-2017-1135.R1 doi


Administration, Topical
Anterior Cruciate Ligament Reconstruction
Antifibrinolytic Agents--administration & dosage
Apoptosis--drug effects
Arthroplasty, Replacement, Knee
Cartilage, Articular--drug effects
Cell Adhesion--drug effects
Cells, Cultured
Chondrocytes--drug effects
Dose-Response Relationship, Drug
Humans
Tranexamic Acid--administration & dosage