Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae.

Vedithi, Sundeep Chaitanya

Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae. [electronic resource] - Scientific reports 03 2018 - 5016 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2045-2322

10.1038/s41598-018-23423-1 doi


Adolescent
Adult
Bacterial Proteins--genetics
DNA, Bacterial--genetics
DNA-Directed RNA Polymerases--genetics
Drug Resistance, Bacterial--genetics
Female
Humans
India
Leprostatic Agents--pharmacology
Leprosy--drug therapy
Male
Microbial Sensitivity Tests
Middle Aged
Mutation
Mycobacterium leprae--drug effects
Protein Binding--genetics
Protein Stability--drug effects
Recurrence
Rifampin--pharmacology
Sequence Analysis, DNA
Structure-Activity Relationship
Treatment Outcome
Young Adult