PaDef defensin from avocado (Persea americana var. drymifolia) is cytotoxic to K562 chronic myeloid leukemia cells through extrinsic apoptosis.

Flores-Alvarez, Luis José

PaDef defensin from avocado (Persea americana var. drymifolia) is cytotoxic to K562 chronic myeloid leukemia cells through extrinsic apoptosis. [electronic resource] - The international journal of biochemistry & cell biology 06 2018 - 10-18 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1878-5875

10.1016/j.biocel.2018.03.013 doi


Anti-Infective Agents--pharmacology
Apoptosis--drug effects
Cell Proliferation--drug effects
Defensins--pharmacology
Female
Gene Expression Regulation, Neoplastic--drug effects
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive--drug therapy
Membrane Potential, Mitochondrial--drug effects
Mitochondria--drug effects
Persea--chemistry
Tumor Cells, Cultured