GAA•TTC repeat expansion in human cells is mediated by mismatch repair complex MutLγ and depends upon the endonuclease domain in MLH3 isoform one.
Halabi, Anasheh
GAA•TTC repeat expansion in human cells is mediated by mismatch repair complex MutLγ and depends upon the endonuclease domain in MLH3 isoform one. [electronic resource] - Nucleic acids research 05 2018 - 4022-4032 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1362-4962
10.1093/nar/gky143 doi
Cells, Cultured
DNA Repeat Expansion
Endonucleases--chemistry
Exons
Friedreich Ataxia--genetics
Gene Knockdown Techniques
HEK293 Cells
Humans
MutL Protein Homolog 1--metabolism
MutL Proteins--chemistry
Protein Domains
Protein Isoforms--metabolism
GAA•TTC repeat expansion in human cells is mediated by mismatch repair complex MutLγ and depends upon the endonuclease domain in MLH3 isoform one. [electronic resource] - Nucleic acids research 05 2018 - 4022-4032 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1362-4962
10.1093/nar/gky143 doi
Cells, Cultured
DNA Repeat Expansion
Endonucleases--chemistry
Exons
Friedreich Ataxia--genetics
Gene Knockdown Techniques
HEK293 Cells
Humans
MutL Protein Homolog 1--metabolism
MutL Proteins--chemistry
Protein Domains
Protein Isoforms--metabolism