Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth

Liu, Ke

Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth [electronic resource] - Molecular cancer therapeutics 05 2018 - 988-1002 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1538-8514

10.1158/1535-7163.MCT-17-0747 doi


A549 Cells
Animals
Antineoplastic Agents--chemistry
Cell Cycle Proteins--antagonists & inhibitors
Cell Line, Tumor
Cell Proliferation--drug effects
Cells, Cultured
Female
Fluorescent Dyes--chemistry
HeLa Cells
Humans
Imidazoles--chemistry
Mice, Inbred BALB C
Mice, Nude
Neoplasms--drug therapy
Nylons--chemistry
Protein Serine-Threonine Kinases--antagonists & inhibitors
Proto-Oncogene Proteins--antagonists & inhibitors
Pyrroles--chemistry
Xenograft Model Antitumor Assays
Polo-Like Kinase 1