Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.
Zhao, Na
Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. [electronic resource] - The Journal of clinical investigation 04 2018 - 1283-1299 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1558-8238
10.1172/JCI95873 doi
Animals
Breast Neoplasms--drug therapy
Cell Line, Tumor
Docetaxel--pharmacology
Drug Delivery Systems
Endoribonucleases--genetics
Female
Humans
Mice
Protein Serine-Threonine Kinases--genetics
Proto-Oncogene Proteins c-myc--genetics
Response Elements
Saccharomyces cerevisiae
Signal Transduction--drug effects
Unfolded Protein Response--drug effects
X-Box Binding Protein 1--genetics
Xenograft Model Antitumor Assays
Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. [electronic resource] - The Journal of clinical investigation 04 2018 - 1283-1299 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1558-8238
10.1172/JCI95873 doi
Animals
Breast Neoplasms--drug therapy
Cell Line, Tumor
Docetaxel--pharmacology
Drug Delivery Systems
Endoribonucleases--genetics
Female
Humans
Mice
Protein Serine-Threonine Kinases--genetics
Proto-Oncogene Proteins c-myc--genetics
Response Elements
Saccharomyces cerevisiae
Signal Transduction--drug effects
Unfolded Protein Response--drug effects
X-Box Binding Protein 1--genetics
Xenograft Model Antitumor Assays