Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication.
Campbell, Grant R
Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication. [electronic resource] - The Journal of biological chemistry 04 2018 - 5808-5820 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1083-351X
10.1074/jbc.RA118.002353 doi
Anti-HIV Agents--pharmacology
Autophagy--drug effects
Azepines--pharmacology
Cell Cycle Proteins
Cells, Cultured
HIV Infections--drug therapy
HIV-1--drug effects
Humans
Imidazoles--pharmacology
Macrophages--drug effects
Nuclear Proteins--antagonists & inhibitors
Phosphatidylinositol 3-Kinase--metabolism
Phosphoinositide-3 Kinase Inhibitors
Protein Kinase Inhibitors--pharmacology
Quinolines--pharmacology
Signal Transduction--drug effects
TOR Serine-Threonine Kinases--antagonists & inhibitors
Transcription Factors--antagonists & inhibitors
Triazoles--pharmacology
Virus Replication--drug effects
Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication. [electronic resource] - The Journal of biological chemistry 04 2018 - 5808-5820 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1083-351X
10.1074/jbc.RA118.002353 doi
Anti-HIV Agents--pharmacology
Autophagy--drug effects
Azepines--pharmacology
Cell Cycle Proteins
Cells, Cultured
HIV Infections--drug therapy
HIV-1--drug effects
Humans
Imidazoles--pharmacology
Macrophages--drug effects
Nuclear Proteins--antagonists & inhibitors
Phosphatidylinositol 3-Kinase--metabolism
Phosphoinositide-3 Kinase Inhibitors
Protein Kinase Inhibitors--pharmacology
Quinolines--pharmacology
Signal Transduction--drug effects
TOR Serine-Threonine Kinases--antagonists & inhibitors
Transcription Factors--antagonists & inhibitors
Triazoles--pharmacology
Virus Replication--drug effects