Impact of SLCO1B1 Genotype on Pediatric Simvastatin Acid Pharmacokinetics.

Wagner, Jonathan B

Impact of SLCO1B1 Genotype on Pediatric Simvastatin Acid Pharmacokinetics. [electronic resource] - Journal of clinical pharmacology 06 2018 - 823-833 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1552-4604

10.1002/jcph.1080 doi


Adolescent
Age Factors
Child
Dose-Response Relationship, Drug
Female
Genotype
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacokinetics
Hyperlipidemias--drug therapy
Liver-Specific Organic Anion Transporter 1--genetics
Male
Polymorphism, Genetic
Simvastatin--analogs & derivatives
Young Adult