Neuroprotective effects of valproic acid on brain ischemia are related to its HDAC and GSK3 inhibitions.

Silva, Monalisa Ribeiro

Neuroprotective effects of valproic acid on brain ischemia are related to its HDAC and GSK3 inhibitions. [electronic resource] - Pharmacology, biochemistry, and behavior 04 2018 - 17-28 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-5177

10.1016/j.pbb.2018.02.001 doi


3,4-Dihydroxyphenylacetic Acid--metabolism
Animals
Brain--metabolism
Brain Ischemia--prevention & control
Cyclooxygenase 2 Inhibitors--pharmacology
Dopamine--metabolism
Dose-Response Relationship, Drug
Glycogen Synthase Kinases--antagonists & inhibitors
Histone Deacetylase Inhibitors--pharmacology
Lipid Peroxidation
Male
Neuroprotective Agents--pharmacology
Nitric Oxide Synthase Type II--metabolism
Nitrites--metabolism
Rats
Valproic Acid--pharmacology