Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis.

Mur, Pilar

Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis. [electronic resource] - Molecular cancer 02 2018 - 23 p. digital

Publication Type: Letter; Research Support, Non-U.S. Gov't

1476-4598

10.1186/s12943-018-0762-8 doi


Adenomatous Polyposis Coli--genetics
Cell Cycle Proteins--chemistry
Colorectal Neoplasms, Hereditary Nonpolyposis--genetics
Germ-Line Mutation
Humans
Models, Molecular
Pedigree
Poly-ADP-Ribose Binding Proteins--chemistry
Protein Conformation
Protein Serine-Threonine Kinases--chemistry
Spindle Apparatus--genetics