Notch signaling regulates Hey2 expression in a spatiotemporal dependent manner during cardiac morphogenesis and trabecular specification.

Miao, Lianjie

Notch signaling regulates Hey2 expression in a spatiotemporal dependent manner during cardiac morphogenesis and trabecular specification. [electronic resource] - Scientific reports 02 2018 - 2678 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

2045-2322

10.1038/s41598-018-20917-w doi


Animals
Basic Helix-Loop-Helix Transcription Factors--biosynthesis
Endocardium--metabolism
Endothelial Cells--metabolism
Female
Gene Knock-In Techniques
Heart--growth & development
Heart Defects, Congenital--genetics
Heart Ventricles--metabolism
Male
Mice
Mice, Knockout
Morphogenesis
Myocardium--metabolism
Pregnancy
Receptor, Notch1--metabolism
Receptors, Notch--metabolism
Repressor Proteins--biosynthesis
Signal Transduction
Spatio-Temporal Analysis