Exenatide modulates metalloproteinase expression in human cardiac smooth muscle cells via the inhibition of Akt signaling pathway.

Gallego-Colon, Enrique

Exenatide modulates metalloproteinase expression in human cardiac smooth muscle cells via the inhibition of Akt signaling pathway. [electronic resource] - Pharmacological reports : PR Feb 2018 - 178-183 p. digital

Publication Type: Journal Article

2299-5684

10.1016/j.pharep.2017.10.003 doi


Cells, Cultured
Cellular Microenvironment
Collagenases--genetics
Coronary Vessels--drug effects
Dose-Response Relationship, Drug
Exenatide
Glucagon-Like Peptide-1 Receptor--metabolism
Humans
Incretins--pharmacology
Matrix Metalloproteinase 1--genetics
Matrix Metalloproteinase 2--genetics
Matrix Metalloproteinase 9--genetics
Muscle, Smooth, Vascular--drug effects
Myocytes, Smooth Muscle--drug effects
Peptides--pharmacology
Phosphorylation
Proto-Oncogene Proteins c-akt--metabolism
Signal Transduction--drug effects
Tissue Inhibitor of Metalloproteinase-1--genetics
Tissue Inhibitor of Metalloproteinase-2--genetics
Tumor Necrosis Factor-alpha--pharmacology
Venoms--pharmacology
Glucagon-Like Peptide-1 Receptor Agonists