Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice.

Meakin, Paul J

Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice. [electronic resource] - Scientific reports 01 2018 - 55 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2045-2322

10.1038/s41598-017-18388-6 doi


Amyloid Precursor Protein Secretases--genetics
Amyloid beta-Peptides--metabolism
Animals
Aspartic Acid Endopeptidases--genetics
Body Weight
Diet, High-Fat
Gene Expression
Glucose--metabolism
Homeostasis
Hypothalamus--metabolism
Leptin--metabolism
Mice
Mice, Knockout
Mice, Obese
Neuropeptides--genetics
Pyramidal Cells--metabolism
Signal Transduction