MiR-449 overexpression inhibits osteogenic differentiation of bone marrow mesenchymal stem cells via suppressing Sirt1/Fra-1 pathway in high glucose and free fatty acids microenvironment.
Qu, Bo
MiR-449 overexpression inhibits osteogenic differentiation of bone marrow mesenchymal stem cells via suppressing Sirt1/Fra-1 pathway in high glucose and free fatty acids microenvironment. [electronic resource] - Biochemical and biophysical research communications 01 2018 - 120-126 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1090-2104
10.1016/j.bbrc.2018.01.009 doi
Cell Differentiation--physiology
Cells, Cultured
Fatty Acids, Nonesterified--metabolism
Glucose--metabolism
Humans
Mesenchymal Stem Cells--cytology
Osteoblasts--cytology
Osteogenesis--physiology
Proto-Oncogene Proteins c-fos--metabolism
Signal Transduction--physiology
Sirtuin 1--metabolism
Stem Cell Niche--physiology
Up-Regulation--physiology
MiR-449 overexpression inhibits osteogenic differentiation of bone marrow mesenchymal stem cells via suppressing Sirt1/Fra-1 pathway in high glucose and free fatty acids microenvironment. [electronic resource] - Biochemical and biophysical research communications 01 2018 - 120-126 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1090-2104
10.1016/j.bbrc.2018.01.009 doi
Cell Differentiation--physiology
Cells, Cultured
Fatty Acids, Nonesterified--metabolism
Glucose--metabolism
Humans
Mesenchymal Stem Cells--cytology
Osteoblasts--cytology
Osteogenesis--physiology
Proto-Oncogene Proteins c-fos--metabolism
Signal Transduction--physiology
Sirtuin 1--metabolism
Stem Cell Niche--physiology
Up-Regulation--physiology