Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain.

Nikolaev, Sergey I

Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain. [electronic resource] - The New England journal of medicine 01 2018 - 250-261 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1533-4406

10.1056/NEJMoa1709449 doi


Adult
Cells, Cultured
DNA Mutational Analysis
Exome
Gene Expression
Human Umbilical Vein Endothelial Cells--metabolism
Humans
Intracranial Arteriovenous Malformations--etiology
MAP Kinase Kinase Kinases--metabolism
MAP Kinase Signaling System
Mutation
Phosphorylation
Proto-Oncogene Proteins p21(ras)--genetics