NQO1 downregulation potentiates menadione-induced endothelial-mesenchymal transition during rosette formation in Fuchs endothelial corneal dystrophy.

Katikireddy, Kishore Reddy

NQO1 downregulation potentiates menadione-induced endothelial-mesenchymal transition during rosette formation in Fuchs endothelial corneal dystrophy. [electronic resource] - Free radical biology & medicine 02 2018 - 19-30 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1873-4596

10.1016/j.freeradbiomed.2017.12.036 doi


Aged
Aged, 80 and over
Cell Differentiation
Cell Line
Cornea--pathology
DNA Damage
Endothelial Cells--physiology
Fibronectins--metabolism
Fuchs' Endothelial Dystrophy--therapy
Gene Expression Regulation
Humans
Mesenchymal Stem Cells--physiology
Middle Aged
NAD(P)H Dehydrogenase (Quinone)--genetics
Oxidative Stress
RNA, Small Interfering--genetics
Reactive Oxygen Species--metabolism
Rosette Formation
Snail Family Transcription Factors--metabolism
Vitamin K 3--metabolism