Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients.
Plenker, Dennis
Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research 03 2018 - 1337-1343 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1557-3265
10.1158/1078-0432.CCR-17-3001 doi
Adenocarcinoma of Lung--diagnosis
Adult
Anaplastic Lymphoma Kinase--antagonists & inhibitors
Crizotinib--pharmacology
Female
Gene Duplication
Gene Rearrangement
Humans
Immunohistochemistry
Male
Middle Aged
Molecular Targeted Therapy
Neoplasm Staging
Oncogene Proteins, Fusion--chemistry
Protein Binding
Protein Interaction Domains and Motifs
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-met--antagonists & inhibitors
Tomography, X-Ray Computed
Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research 03 2018 - 1337-1343 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1557-3265
10.1158/1078-0432.CCR-17-3001 doi
Adenocarcinoma of Lung--diagnosis
Adult
Anaplastic Lymphoma Kinase--antagonists & inhibitors
Crizotinib--pharmacology
Female
Gene Duplication
Gene Rearrangement
Humans
Immunohistochemistry
Male
Middle Aged
Molecular Targeted Therapy
Neoplasm Staging
Oncogene Proteins, Fusion--chemistry
Protein Binding
Protein Interaction Domains and Motifs
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-met--antagonists & inhibitors
Tomography, X-Ray Computed