Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains.
Hoffman, Gabriel E
Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains. [electronic resource] - Nature communications 12 2017 - 2225 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
2041-1723
10.1038/s41467-017-02330-5 doi
Adolescent
Adult
Antigens, Surface--genetics
Autopsy
Brain--metabolism
Case-Control Studies
Child
DNA Copy Number Variations
Female
Humans
Induced Pluripotent Stem Cells--metabolism
Linear Models
Male
Nanog Homeobox Protein--genetics
Nestin--genetics
Neural Stem Cells--metabolism
Neurons--metabolism
Octamer Transcription Factor-3--genetics
Proteoglycans--genetics
RNA, Messenger--metabolism
SOXB1 Transcription Factors--genetics
Schizophrenia--genetics
Sequence Analysis, RNA
Stage-Specific Embryonic Antigens--genetics
Synapsins--genetics
Transcriptome
Young Adult
Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains. [electronic resource] - Nature communications 12 2017 - 2225 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
2041-1723
10.1038/s41467-017-02330-5 doi
Adolescent
Adult
Antigens, Surface--genetics
Autopsy
Brain--metabolism
Case-Control Studies
Child
DNA Copy Number Variations
Female
Humans
Induced Pluripotent Stem Cells--metabolism
Linear Models
Male
Nanog Homeobox Protein--genetics
Nestin--genetics
Neural Stem Cells--metabolism
Neurons--metabolism
Octamer Transcription Factor-3--genetics
Proteoglycans--genetics
RNA, Messenger--metabolism
SOXB1 Transcription Factors--genetics
Schizophrenia--genetics
Sequence Analysis, RNA
Stage-Specific Embryonic Antigens--genetics
Synapsins--genetics
Transcriptome
Young Adult