Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype.
Plastira, I
Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype. [electronic resource] - Journal of neuroinflammation Dec 2017 - 253 p. digital
Publication Type: Journal Article
1742-2094
10.1186/s12974-017-1024-1 doi
Animals
Animals, Newborn
Carboxylic Acids--pharmacology
Cell Movement--drug effects
Cells, Cultured
Cerebral Cortex--cytology
Cytokines--genetics
Enzyme Inhibitors--pharmacology
Lysophospholipids--pharmacology
Mice
Mice, Inbred C57BL
Microglia--drug effects
Neurons--drug effects
Phosphorylation
Protein Kinase C--genetics
Pyrimidines--pharmacology
RNA, Small Interfering--genetics
Reactive Oxygen Species--metabolism
Receptors, Lysophosphatidic Acid--antagonists & inhibitors
Signal Transduction--drug effects
Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype. [electronic resource] - Journal of neuroinflammation Dec 2017 - 253 p. digital
Publication Type: Journal Article
1742-2094
10.1186/s12974-017-1024-1 doi
Animals
Animals, Newborn
Carboxylic Acids--pharmacology
Cell Movement--drug effects
Cells, Cultured
Cerebral Cortex--cytology
Cytokines--genetics
Enzyme Inhibitors--pharmacology
Lysophospholipids--pharmacology
Mice
Mice, Inbred C57BL
Microglia--drug effects
Neurons--drug effects
Phosphorylation
Protein Kinase C--genetics
Pyrimidines--pharmacology
RNA, Small Interfering--genetics
Reactive Oxygen Species--metabolism
Receptors, Lysophosphatidic Acid--antagonists & inhibitors
Signal Transduction--drug effects