Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy.

Chowell, Diego

Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy. [electronic resource] - Science (New York, N.Y.) 02 2018 - 582-587 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1095-9203

10.1126/science.aao4572 doi


Adult
Aged
Antigen Presentation
Antigens, Neoplasm--immunology
CD8-Positive T-Lymphocytes--immunology
CTLA-4 Antigen--antagonists & inhibitors
Cancer Vaccines--immunology
Cohort Studies
Genetic Carrier Screening
Histocompatibility Antigens Class I--chemistry
Humans
Immunotherapy--methods
Melanoma--genetics
Middle Aged
Programmed Cell Death 1 Receptor--antagonists & inhibitors
Protein Conformation
Skin Neoplasms--genetics
Treatment Outcome
Young Adult