Aging and neurodegeneration are associated with increased mutations in single human neurons.

Lodato, Michael A

Aging and neurodegeneration are associated with increased mutations in single human neurons. [electronic resource] - Science (New York, N.Y.) 02 2018 - 555-559 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1095-9203

10.1126/science.aao4426 doi


Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Aging--genetics
Child
Child, Preschool
Cockayne Syndrome--genetics
DNA Mutational Analysis
DNA Repair--genetics
Female
Hippocampus--cytology
Humans
Infant
Male
Middle Aged
Mutation Rate
Neurodegenerative Diseases--genetics
Neurogenesis--genetics
Neurons
Prefrontal Cortex--cytology
Single-Cell Analysis
Whole Genome Sequencing
Xeroderma Pigmentosum--genetics
Young Adult