Inhibition of Farnesyltransferase Potentiates NOTCH-Targeted Therapy against Glioblastoma Stem Cells.
Ma, Yufang
Inhibition of Farnesyltransferase Potentiates NOTCH-Targeted Therapy against Glioblastoma Stem Cells. [electronic resource] - Stem cell reports 12 2017 - 1948-1960 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
2213-6711
10.1016/j.stemcr.2017.10.028 doi
Amyloid Precursor Protein Secretases--antagonists & inhibitors
Animals
Cell Line, Tumor
Cell Self Renewal--drug effects
Disease Progression
Drug Resistance, Neoplasm--genetics
Enzyme Inhibitors--administration & dosage
Farnesyltranstransferase--antagonists & inhibitors
Gene Expression Regulation, Neoplastic--drug effects
Glioblastoma--drug therapy
Humans
Mice
Molecular Targeted Therapy
Neoplastic Stem Cells--drug effects
Radiation Tolerance--drug effects
Receptors, Notch--antagonists & inhibitors
Xenograft Model Antitumor Assays
Inhibition of Farnesyltransferase Potentiates NOTCH-Targeted Therapy against Glioblastoma Stem Cells. [electronic resource] - Stem cell reports 12 2017 - 1948-1960 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
2213-6711
10.1016/j.stemcr.2017.10.028 doi
Amyloid Precursor Protein Secretases--antagonists & inhibitors
Animals
Cell Line, Tumor
Cell Self Renewal--drug effects
Disease Progression
Drug Resistance, Neoplasm--genetics
Enzyme Inhibitors--administration & dosage
Farnesyltranstransferase--antagonists & inhibitors
Gene Expression Regulation, Neoplastic--drug effects
Glioblastoma--drug therapy
Humans
Mice
Molecular Targeted Therapy
Neoplastic Stem Cells--drug effects
Radiation Tolerance--drug effects
Receptors, Notch--antagonists & inhibitors
Xenograft Model Antitumor Assays