Prediction of metabolism-induced hepatotoxicity on three-dimensional hepatic cell culture and enzyme microarrays.

Yu, Kyeong-Nam

Prediction of metabolism-induced hepatotoxicity on three-dimensional hepatic cell culture and enzyme microarrays. [electronic resource] - Archives of toxicology Mar 2018 - 1295-1310 p. digital

Publication Type: Journal Article

1432-0738

10.1007/s00204-017-2126-3 doi


Animals
Carcinoma, Hepatocellular--pathology
Cell Culture Techniques--methods
Cell Line, Tumor
Chemical and Drug Induced Liver Injury--etiology
Enzymes--analysis
High-Throughput Screening Assays--instrumentation
Humans
Inhibitory Concentration 50
Lab-On-A-Chip Devices
Lethal Dose 50
Liver Neoplasms--pathology
Miniaturization
Protein Array Analysis--instrumentation
Rats
Sensitivity and Specificity
Toxicity Tests--instrumentation