Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.

Brouwer, Jason M

Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. [electronic resource] - Molecular cell Nov 2017 - 659-672.e9 p. digital

Publication Type: Journal Article

1097-4164

10.1016/j.molcel.2017.11.001 doi


Animals
Apoptosis--drug effects
Bcl-2-Like Protein 11--chemistry
Cell Line, Transformed
Humans
Mice
Mitochondria--genetics
Peptides--chemistry
Protein Binding
Structure-Activity Relationship
bcl-2 Homologous Antagonist-Killer Protein--chemistry