20(S)-protopanaxadiol (PPD) alleviates scopolamine-induced memory impairment via regulation of cholinergic and antioxidant systems, and expression of Egr-1, c-Fos and c-Jun in mice.

Lu, Cong

20(S)-protopanaxadiol (PPD) alleviates scopolamine-induced memory impairment via regulation of cholinergic and antioxidant systems, and expression of Egr-1, c-Fos and c-Jun in mice. [electronic resource] - Chemico-biological interactions Jan 2018 - 64-72 p. digital

Publication Type: Journal Article

1872-7786

10.1016/j.cbi.2017.11.008 doi


Animals
Antioxidants--metabolism
Dose-Response Relationship, Drug
Drug Administration Schedule
Early Growth Response Protein 1--genetics
Gene Expression Regulation--drug effects
Hippocampus--drug effects
JNK Mitogen-Activated Protein Kinases--genetics
Maze Learning--drug effects
Memory Disorders--chemically induced
Mice
Parasympathetic Nervous System--drug effects
Proto-Oncogene Proteins c-fos--genetics
Sapogenins--administration & dosage
Scopolamine--toxicity