Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.
Fan, Ying
Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils. [electronic resource] - The Biochemical journal 01 2018 - 23-44 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1470-8728
10.1042/BCJ20170803 doi
Animals
Antibodies, Monoclonal--chemistry
Antibodies, Phospho-Specific--chemistry
Antibody Specificity
Case-Control Studies
Clinical Trials as Topic
Enzyme Assays
Epitopes--chemistry
Gene Expression Regulation
Genetic Predisposition to Disease
Gyrus Cinguli--immunology
Humans
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2--antagonists & inhibitors
Leukocytes, Mononuclear--immunology
Mutation
Neutrophils--immunology
Parkinson Disease--enzymology
Phosphorylation
Protein Kinase Inhibitors--pharmacology
Rabbits
Signal Transduction
rab GTP-Binding Proteins--chemistry
Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils. [electronic resource] - The Biochemical journal 01 2018 - 23-44 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1470-8728
10.1042/BCJ20170803 doi
Animals
Antibodies, Monoclonal--chemistry
Antibodies, Phospho-Specific--chemistry
Antibody Specificity
Case-Control Studies
Clinical Trials as Topic
Enzyme Assays
Epitopes--chemistry
Gene Expression Regulation
Genetic Predisposition to Disease
Gyrus Cinguli--immunology
Humans
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2--antagonists & inhibitors
Leukocytes, Mononuclear--immunology
Mutation
Neutrophils--immunology
Parkinson Disease--enzymology
Phosphorylation
Protein Kinase Inhibitors--pharmacology
Rabbits
Signal Transduction
rab GTP-Binding Proteins--chemistry