Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase.

Asquith, Christopher R M

Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase. [electronic resource] - ChemMedChem 01 2018 - 48-66 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1860-7187

10.1002/cmdc.201700663 doi


Aniline Compounds--chemistry
Binding Sites
Catalytic Domain
Drug Design
Endocytosis--drug effects
Humans
Intracellular Signaling Peptides and Proteins--antagonists & inhibitors
Kinetics
Molecular Docking Simulation
Protein Binding
Protein Kinase Inhibitors--chemistry
Protein Serine-Threonine Kinases--antagonists & inhibitors
Quinazolines--chemistry
Structure-Activity Relationship
Viruses--pathogenicity