6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury.
Delehouzé, C
6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury. [electronic resource] - Scientific reports 10 2017 - 12931 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2045-2322
10.1038/s41598-017-12788-4 doi
Aorta--cytology
Apoptosis--drug effects
Cell Death--drug effects
Cell Hypoxia--drug effects
Cold Temperature
Cytoprotection--drug effects
Endothelial Cells--cytology
Humans
Models, Molecular
Necrosis
Oxygen--adverse effects
Protein Kinase Inhibitors--pharmacology
Receptor-Interacting Protein Serine-Threonine Kinases--antagonists & inhibitors
Receptors, Death Domain--metabolism
Small Molecule Libraries--pharmacology
6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury. [electronic resource] - Scientific reports 10 2017 - 12931 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2045-2322
10.1038/s41598-017-12788-4 doi
Aorta--cytology
Apoptosis--drug effects
Cell Death--drug effects
Cell Hypoxia--drug effects
Cold Temperature
Cytoprotection--drug effects
Endothelial Cells--cytology
Humans
Models, Molecular
Necrosis
Oxygen--adverse effects
Protein Kinase Inhibitors--pharmacology
Receptor-Interacting Protein Serine-Threonine Kinases--antagonists & inhibitors
Receptors, Death Domain--metabolism
Small Molecule Libraries--pharmacology