ROS generation and JNK activation contribute to 4-methoxy-TEMPO-induced cytotoxicity, autophagy, and DNA damage in HepG2 cells.
Zhang, Zhuhong
ROS generation and JNK activation contribute to 4-methoxy-TEMPO-induced cytotoxicity, autophagy, and DNA damage in HepG2 cells. [electronic resource] - Archives of toxicology Feb 2018 - 717-728 p. digital
Publication Type: Journal Article
1432-0738
10.1007/s00204-017-2084-9 doi
Acetylcysteine--pharmacology
Anthracenes--pharmacology
Autophagy--drug effects
Comet Assay
Cyclic N-Oxides--toxicity
DNA Damage
Hep G2 Cells
Humans
JNK Mitogen-Activated Protein Kinases--metabolism
MAP Kinase Signaling System
Oxidative Stress--drug effects
Reactive Oxygen Species--metabolism
ROS generation and JNK activation contribute to 4-methoxy-TEMPO-induced cytotoxicity, autophagy, and DNA damage in HepG2 cells. [electronic resource] - Archives of toxicology Feb 2018 - 717-728 p. digital
Publication Type: Journal Article
1432-0738
10.1007/s00204-017-2084-9 doi
Acetylcysteine--pharmacology
Anthracenes--pharmacology
Autophagy--drug effects
Comet Assay
Cyclic N-Oxides--toxicity
DNA Damage
Hep G2 Cells
Humans
JNK Mitogen-Activated Protein Kinases--metabolism
MAP Kinase Signaling System
Oxidative Stress--drug effects
Reactive Oxygen Species--metabolism