Synthesis, biological activity, and conformational analysis of (2S,3R,4S)-MeBmt1-cyclosporin, a novel 1-position epimer of cyclosporin A.

Rich, D H

Synthesis, biological activity, and conformational analysis of (2S,3R,4S)-MeBmt1-cyclosporin, a novel 1-position epimer of cyclosporin A. [electronic resource] - Journal of medicinal chemistry Aug 1989 - 1982-7 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0022-2623

10.1021/jm00128a048 doi


Chemical Phenomena
Chemistry
Concanavalin A--antagonists & inhibitors
Cyclosporins--chemical synthesis
Immunosuppressive Agents--chemical synthesis
Lymphocyte Activation--drug effects
Magnetic Resonance Spectroscopy
Stereoisomerism
Structure-Activity Relationship