N-glycolylneuraminic acid knockout reduces erythrocyte sequestration and thromboxane elaboration in an ex vivo pig-to-human xenoperfusion model.

Cimeno, Arielle

N-glycolylneuraminic acid knockout reduces erythrocyte sequestration and thromboxane elaboration in an ex vivo pig-to-human xenoperfusion model. [electronic resource] - Xenotransplantation 11 2017

Publication Type: Journal Article

1399-3089

10.1111/xen.12339 doi


Animals
Animals, Genetically Modified
Galactosyltransferases--genetics
Gene Knockout Techniques--methods
Graft Survival--immunology
Heterografts--drug effects
Humans
Membrane Cofactor Protein--genetics
Neuraminic Acids--pharmacology
Swine
Thrombocytopenia--therapy
Transplantation, Heterologous