MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death.

Dondelinger, Yves

MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death. [electronic resource] - Nature cell biology Oct 2017 - 1237-1247 p. digital

Publication Type: Journal Article

1476-4679

10.1038/ncb3608 doi


Animals
Apoptosis--drug effects
Cell Line
Cytosol--enzymology
Disease Models, Animal
Enzyme Activation
Female
Fibroblasts--drug effects
Intracellular Signaling Peptides and Proteins--antagonists & inhibitors
Mice
Mice, Inbred C57BL
Necrosis
Phosphorylation
Protein Kinase Inhibitors--pharmacology
Protein Serine-Threonine Kinases--antagonists & inhibitors
Receptor-Interacting Protein Serine-Threonine Kinases--antagonists & inhibitors
Receptors, Tumor Necrosis Factor, Type I--agonists
Serine
Shock--chemically induced
Signal Transduction--drug effects
Time Factors
Tumor Necrosis Factor-alpha--toxicity